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KMID : 0812020010070020251
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Korean Journal of Neurogastroenterology and Motility
2001 Volume.7 No. 2 p.251 ~ p.256
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A Case of Colonic Pseudo-Obstruction in a Patient with Parkinson's Disease
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추교영/Kyo Young Choo
최명규/최황/방춘상/최규용/정인식/정규원/선희식/Myung Gyu Choi/Hwang Choi/Choon Sang Bhang/Kyu Yong Choi/In Sik Chung/Kyu Won Chung/Hee Sik Sun
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Abstract
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Colonic pseudo-obstruction (CPO) is a syndrome characterized by obstructive symptoms and signs without mechanical obstruction. Parkinson's disease is one of the various clinical situations developing CPO. Recently, one study group reported that
neostigmine was significantly more effective than placebo in rapidly decreasing colonic dilatation in the majority of patients with acute CPO. We experienced a 69-year-old male patient with Parkinson's disease who complained abdominal distension.
There
was a marked colonic dilatation on plain abdominal radiographs without mechanical obstruction. Colonic dilatation failed to improve with conservative management. Immediate clinical response was achieved after patient received 2.0 ㎎ of
neostigmine
intravenously under monitoring by electrocardiography. One month later, he had recurrent colonic dilatation, but no clinical response to second administration of neostigmine, leading to colonic decompression. After a third recurrence of colonic
dilatation, the patient was refractory to conservative management, and he underwent surgical treatment.
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